Friday, November 14, 2008

Acid supplements Folat Lower Stroke Risk


Based on the results of a meta-analysis of research, known folat that acid supplements can reduce the risk of stroke by 18% - 25%. However, the benefits for other cardiovascular conditions have not yet clearly known.

Reduction in stroke risk appears from a meta-analysis of eight random trial that observed suplementasi acid folat, with or without other B vitamins. The study was conducted by scientists from Northwestern University, and the results reported in the journal The Lancet.

In the multilevel analysis of the trial include 16,841 men and women, researchers divide the group into:
â € ¢ sub-groups that receive folat acid supplements for more than 3 years
â € ¢ Sub-groups which have homosistein rate decreased by 20% or more
â € ¢ Sub-groups living in areas without Fortification acid folat

The study determined that patients with various disease often experience a lack of folat acid, B vitamins (such as vitamin B12 and vitamin B6), and the fatty acid Omega-3 (especially DHA).

To-eight patients entered the trial with the initial conditions, namely a trial with a history of stroke and seven others with the disease and coronary heart disease or end-stage renal displasia esofagus. Decrease the risk of stroke overall is as much as 18%. In addition, the risk of stroke 25% lower on 7 trial that there was no history of stroke.

Although it has been proven that folat acid supplements can reduce the risk of stroke, debate continues whether the acid folat can improve the outcome of the assessment of cardiovascular end. Some studies found that contrary to the results, while epidemiological studies support the proposal that the risk factors and different power relationship between stroke and cardiovascular disease. The researchers speculate, although the reasons for the differences are not entirely understood, they refer to the fact that more stroke associated with pathology in the small blood vessels, while cardiovascular disease tend to involve large blood vessels.

The clinical trial is expected next can be done without Fortification in the region and among individuals without a history of stroke and to test the effectiveness of causal relationship between suplementasi acid folat the stroke.

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